By definition, proteomics describes the technology that is able to identify proteins expressed from a genome at a certain time point under strictly defined conditions, the proteome.
Differential quantitative analysis of protein expression patterns of tissues or body fluids of diseased/non-diseased species or cellular systems, treated under different conditions, allows to identify sets of proteins that are specifically related to those states.
Since different technologies produce in many cases different but often complementary data, no single approach to differential analysis provides a comprehensive view into a biological system.
Toplab has established a set of technologies to generate comprehensive protein profiles from multiplexed samples (e.g. one normal versus diseased or treated) in order to identify proteins that are unique for a specific proteome.
The methods cover all classical methods like 2D-PAGE, 2D-DIGE, as well as ICPL, iTRAQ or targeted proteomics methods like SRM (selective reaction monitoring)